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The method has the advantages that Fmoc-Lys (Alloc)-OH protection amino acid is used as a raw material, de-protection is carried out by the aid of selected Pd (PPh3) 4, accordingly, operation procedures are simple, only 1-2 times of simple elimination reaction operation are required, each elimination reaction operation is carried out for 10-30 min, side reaction is prevented, the operation procedures are safe, and enlarged production can be facilitated

Nat Commun 14 , 2569 (2023)

"This bill is a reaction to a very serious problem in the state of Kentucky

(169) showed diabetic animal models administered berberine activates the Nrf2 pathway and decreases OxS